GLUTS TRANSPORTADORES DE GLUCOSA PDF

cómo se transporta la glucosa través de la membrana celular? diana díaz hernández, luis carlos burgos herrera de la célula para su ingreso requiere una. RESUMEN El transporte de la glucosa a través de la membrana plasmática de a sodio (SGLT) y los sistemas facilitadores del transporte de glucosa (GLUT). Se han descrito dos sistemas de transporte de glucosa y de otros monosacáridos : y los transportadores de glucosa llamados GLUT (glucosa transporters).

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Transportaores and characterization of the major insulin-responsive glucose transporter expressed in human skeletal muscle and other insulin-responsive tissues. Mammaliam facilitative glucose transporters: Decreased glucose transporter GLUT 4 content in insulin-sensitive tissues of obese aurothioglucose- and monosodium glutamate-treated mice.

Is widely distributed in fetal tissues. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease.

Is a bidirectional transporter, allowing glucose to flow in 2 directions.

These studies have revealed that, in DM2, the GLUT4 content is drastically reduced, playing an important role in insulin resistance. Molecular physiology of sodium-glucose cotransporters.

Transportador de glucosa

Is a high-frequency and low-affinity isoform. J Cell Biol ; Transcription repressed by glucose. Defective glucose transport across the blood-brain barrier as a cause of persistent hypoglcyrrachia, seizures, and developmental delay.

Braz J Med Biol Res ; Czech Academy of SciencesPrague,pp.

Transportadores de glucosa by Jose Rodriguez on Prezi

The key point here was ‘flux coupling’, the cotransport of sodium and glucose in the apical membrane of the small intestinal epithelial cell. In other projects Wikimedia Commons. It is also present in the basolateral membrane of the small intestine epithelium.

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Vesicular glutamate transporter 1 SLC32A1. In obesity, the GLUT4 content is not diminished providing that insulin sensitiveness is preserved. Views Read Edit View history.

J Biol Chem ; GLUT1 expression is upregulated in many tumors. In the adult, it is expressed at highest levels in erythrocytes and also in the endothelial cells of barrier tissues such as the blood—brain barrier.

Proceedings of a Symposium held in Glufosa, August 22—27, Nucleotide sequence of putP, the proline transoortadores of Escherichia coli K A Cellular And Molecular Approaoch.

Close genetic linkage between HLA and renal glycosuria. Most non- autotrophic cells are unable to produce free glucose because they lack expression of glucosephosphatase and, thus, are involved only in glucose uptake and catabolism.

Annu Rev Physiol ; However, it is responsible for the low level of basal glucose uptake required to sustain respiration in all cells. J Clin Invest ; Phloretin Phlorizin T TA. Expressed mostly in neurons where it is believed to be the main glucose transporter isoformand in the placenta.

In Lguts cerevisiae glucose transport takes place through facilitated diffusion.

Transporgadores glucose is a vital source of energy for all life, these transporters are present in all phyla. Fructose transporter in human spermatozoa and small intestine is GLUT5. This hypothesis was rapidly tested, refined, and extended [to] encompass the active transport of a diverse range of molecules and ions into virtually every cell type.

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GLUT is a type of uniporter transporter protein.

Transpotadores expressed by renal tubular cells, liver cells and pancreatic beta cells. From Wikipedia, the free encyclopedia. GLUTs are integral membrane proteins that contain 12 membrane-spanning helices with both the amino and carboxyl termini exposed on the cytoplasmic side of the plasma membrane. Physiol Rev ; Evidence for a family of human glucose transporter-like proteins.

Glucose transporter

Quantification of GLUT4 transporter in insulin-sensitive tissues from pinealectomized rats. Cloning of a human cDNA with similarity to the sodium-glucose cotransporter. Efeito do diabetes sobre os transportadores de glicose de epitelio renal. GLUT proteins transport glucose and related hexoses according to a model of alternate conformation, [5] [6] [7] which predicts that the transporter exposes a single substrate binding site toward either the outside or the inside of the cell.

By group SLC1—10 1: Is a high-affinity isoform, allowing it to transport even in times of low glucose concentrations.